Anxiety and Extraversion in Lupus-Related Atherosclerosis

The interaction of extraversion and anxiety sensitivity on social anxiety: evidence of specificity relative to depression.

Neuroticism and extraversion have been linked to the etiologies and course of anxiety and mood disorders, such that neuroticism is broadly associated with numerous disorders and extraversion is most strongly associated with social anxiety and depression. While previous research has established the broad associations between temperament and emotional disorders, less is known about the specific, ...

Hemorheological parameters are related to subclinical atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis patients.

OBJECTIVES Rheological characteristics of blood are strongly linked to atherothrombosis in the general population, but its contribution to atherosclerosis in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) is currently unclear. This work examines the relationship between blood rheology, traditional cardiovascular (CV) risk factors, inflammation and subclinical atherosclerosis i...

Atherosclerosis, autoimmunity, and systemic lupus erythematosus.

Atherosclerosis can be considered a chronic inflammatory condition of the vessel wall. Fatty streaks, the earliest morphological lesions of atherosclerosis, are caused by lipids (primarily of cholesteryl esters) accumulated within the macrophages (foam cells) and smooth muscle cells in the intimal layer. These lesions progress into atherosclerotic plaques containing extracellular matrix compone...

Studies of Atherosclerosis in Systemic Lupus Erythematosus

Aortic Atherosclerosis in Systemic Lupus Erythematosus

Aortic atherosclerosis (AoA) defined as intima-media thickening or plaques and aortic stiffness (AoS) also considered an atherosclerotic process and defined as decreased vessel distensibility (higher pulse pressure to achieve similar degree of vessel distension) are common in patients with SLE. Immune-mediated inflammation, thrombogenesis, traditional atherogenic factors, and therapy-related me...